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. 2017 Nov 13;8:1469. doi: 10.1038/s41467-017-01747-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Principal component analysis (PCA) of the 16 heart regions based on their proteomic expression profiles. a The proteomes of the cavities (RA, LA, RV, LV, SepA, and SepV), vessels (Ao, PA, RCA, LCA, IVC, and PVe), and valves (TV, MV, AV, and PV) depicted by replicate number (individuals 1, 2, and 3). The first and second component segregate the heart areas and account for 32.3 and 9% of the variability, respectively. b Proteins driving the segregation between the three heart areas. c Cavities segregate into the ventricular and atrial part, d vessels into coronary arteries (RCA, LCA) and outgoing vessels (Ao, PA), and e valves into ventricular (MV, TV) and semilunar valves (AV, PV)