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. 2017 Nov 13;8:1469. doi: 10.1038/s41467-017-01747-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Clinical application of the healthy human heart atlas to atrial fibrillation. a Experimental workflow: LA tissues from three atrial fibrillation patients (AFib) were single-runs of technical triplicates. Data were matched against the healthy human LA library. b Volcano plot of the p values vs. the log2 protein abundance differences in AFib compared to healthy LA. Significantly up- and downregulated proteins are highlighted in red and blue, respectively (FDR 0.05)