FIGURE 7.

Effects of VOA on enterogenous endotoxin and intestinal mucosal barrier regulation. (A) LPS in hepatic portal veins, n = 6 was increased after 5-FU. VOA and BA blocked increases in LPS, (B) ZO-1, n = 6, and (C) occludin, n = 6. In the histogram, the data of the horizontal coordinate that were more than 10¹ were counted and were used as original data to draw the bar chart. The histograms of ZO-1 and occludin show a decrease after 5-FU. VOA and BA increased proteins (p < 0.01 and p < 0.001). Values are means ± SD. ^∗ Significant difference compared to the controls. ^# Significant difference compared to the model and controls. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^#p < 0.05, ^##p < 0.01, and ^###p < 0.001.