Table 2 Univariate and a multivariate hazard ratios for death or amputation of limb.
| Death or Amputation n (%) | Univariate HR (95%CI) p-value | Multivariate HR(95%CI) p-value | Regression coefficient | Score | |
|---|---|---|---|---|---|
| Age ≧75 years | 10/53 (18.9) | 1.51 (0.94–2.45) p=0.09 | 1.49 (0.74–2.98) p=0.27 | 0.40 | 1 |
| Male | 41/188 (21.8) | 0.99 (0.65–1.50) p=0.99 | — | — | — |
| Hypertension | 31/149 (20.8) | 0.97 (0.66–1.43) p=0.89 | — | — | — |
| Hypercholesterolemia | 14/53 (26.4) | 1.31 (0.82–2.10) p=0.26 | — | — | — |
| Diabetes | 14/53 (21.6) | 1.19 (0.81–1.77) p=0.37 | — | — | — |
| Coronary artery disease | 54/249 (21.7) | 1.04 (0.55–1.94) p=0.91 | — | — | — |
| Non-ambulation | 45/129 (34.9) | 3.80 (2.52–5.74) p<0.01 | 2.42 (1.30–4.51) p<0.01 | 0.88 | 3 |
| Ulcer/Gangrene | 40/143 (28.0) | 2.19 (1.45–3.31) p<0.01 | 1.68 (0.93–3.05) p=0.09 | 0.52 | 2 |
| GNRI <92 | 30/117 (25.6) | 2.63 (1.52–4.56) p=0.01 | 1.91 (1.08–3.39) p=0.03 | 0.65 | 2 |
| CRP >0.3 mg/dl | 43/155 (27.7) | 2.71 (1.68–4.38) p<0.01 | 1.49 (0.79–2.80) p=0.22 | 0.40 | 1 |
| Hematocrit ≦30% | 19/78 (24.4) | 1.54 (1.02–2.32) p=0.04 | * | — | — |
| Platelet | — | 1.01 (0.98–1.03) p=0.64 | — | — | — |
*Hematocrit was excluded from the variables due to a negative regression coefficient in the multivariate analysis. HR: hazard ratio; GNRI: geriatric nutritional risk index; CI: confidence interval