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. 2017 Nov 13;7:15380. doi: 10.1038/s41598-017-15336-2

Table 3.

List of 25 BJ04 amino acid (AA) residues that were not found in any prototype sequences.

ORF Name Length(AA) AA change Genomic positiona Other 30 GB sequencesb PROVEAN analysisc
Control protein E1A 289 A29T 643 2 NDd
Control protein E1B 55 K 495 T51A 2157 5 ND
DNA polymerase 1198 V89I 8519 0 Neutral
N254H 8024 0 Neutral
R274C 7964 0 Deleterious
Terminal protein precursor pTP 671 A64T 10399 0 Neutral
A283T 9742 0 Neutral
D432N 9313 1 ND
A527T 9028 1 ND
Encapsidation protein 52 K 415 P74S 11259 0 Neutral
Capsid protein precursor pIIIa 585 L474V 13727 0 Neutral
Penton base 571 A368T 15266 3 ND
Single-stranded DNA-binding protein 529 R67C 23881 0 Neutral
Hexon assembly protein 100 K 805 A122T 24471 0 Neutral
Encapsidation protein 22 K 195 S75N 26462 0 Neutral
Protein 33 K 228 S75N 26462 0 Neutral
Control protein E3 12.5 K 107 T50I 28047 0 Neutral
Membrane glycoprotein E3 gp19K 159 K62R 28995 0 Neutral
Fiber 582 S178T 31561 5 ND
Control protein E4orf6/7 150 P66S 33171 10 ND
Q69R 33161 9 ND
Control protein E4 34 K 294 Y61F 33896 5 ND
L90I 33810 0 Neutral
Control protein E4orf4 114 H38R 34230 0 Neutral
Control protein E4orf3 116 V70I 34499 0 Neutral

Note: aGenomic positions as well as amino changes for each ORF were indicated.

bThe number of sequences within the remaining 30 GB sequences featuring the same amino change is shown.

cThe PROVEAN prediction on the effect of amino changes only found in BJ04 is indicated.

dNot done (ND).