Table 1.
Characteristics of the study population with available follow-up data (n = 289)
| Placebo (n = 136) |
Vitamin D (n = 153) |
|
|---|---|---|
| Age, years | 62.2 ± 14.5 | 60.3 ± 16.3 |
| Female, n (%) | 51 (37.5%) | 54 (35.3%) |
| Body mass index, kg/m2 | 27.5 ± 6.0 | 27.8 ± 5.1 |
| Charlson comorbidity index | 2.8 ± 2.2 | 2.6 ± 2.2 |
| SAPS II at ICU admission | 24.9 ± 19.1 | 21.7 ± 17.1 |
| TISS-28 at study inclusion | 36.9 ± 7.6 | 36.8 ± 7.3 |
| Admission diagnosis, n (%) | ||
| Sepsis | 11 (8.1%) | 12 (7.8%) |
| Cardiovascular | 21 (15.4%) | 18 (11.8%) |
| Neurologic | 32 (23.5%) | 38 (24.8%) |
| Other non-surgical | 15 (11.1%) | 15 (9.9%) |
| Cardiosurgical | 25 (18.4%) | 29 (19.0%) |
| Trauma | 14 (10.3%) | 20 (13.1%) |
| Other surgical | 18 (13.2%) | 21 (13.9%) |
| At study inclusion | ||
| Mechanical ventilation, n (%) | 100 (73.5%) | 114 (74.5%) |
| Norepinephrine use, n (%) | 73 (53.7%) | 82 (53.6%) |
Notes: Plus-minus values are means ± SD. The Charlson comorbidity index predicts 10-year mortality and is a sum calculated from 22 comorbid conditions with each assigned a score of 1, 2, 3, or 6. The Simplified Acute Physiology Score (SAPS II) is a point score measuring the severity of disease for patients admitted to the intensive care unit. It is calculated from 12 routine physiological measurements and ranges from 0 to 163 with higher scores indicating higher disease severity. Therapeutic Intervention Scoring System (TISS) measures the extent of nursing workload with a maximum TISS-28 score of 78. A higher score indicates a higher nursing workload
Abbreviations: ICU intensive care unit