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. 2017 Nov 14;8:1477. doi: 10.1038/s41467-017-01432-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Primacy coding of odor identity. a Schematic presentation of the patterns of glomerulus (OSN) activation for three concentrations of the same odor. The total number of active glomeruli increases with an increase of odor concentration. b The temporal profiles of the odor concentration in the nose during inhalation for three concentrations of the presented stimuli. Dashed lines represent concentration thresholds for representative glomeruli (horizontal) and corresponding response latencies (vertical). c Temporal sequence of glomeruli activation for three different odor concentrations. d Optogenetic mask schematic demonstrating the effect of the optogenetic mask on temporal sequences when presented late and early relative to odor-evoked temporal pattern