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. 2017 Nov 13;7:15438. doi: 10.1038/s41598-017-15510-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Interaction networks of microbes in the Indian samples. (A) Negative interaction network of microbial genera showing Helicobacter as lone hub. (B) Negative interaction network at OTU level showing similar trends and H. pylori acting as hub node. (C) Co-occurrence network showing interaction specificity of bacterial genera. Orange nodes correspond to microbes belonging to clade C1 and green nodes correspond to members of cluster C2. (D) Co-occurrence network of OTUs, showing similar associations.