Table 1.
Expression of vessel identity markers in mouse AVF compared to sham veins, days 7 and 21 (n = 8).
Marker | p-value* | 7 days | p-value** | 21 days | p-value** |
---|---|---|---|---|---|
Venous | |||||
Eph-B4 | <0.0001 | 2.605 ± 0.3456 | 0.0002 | 1.754 ± 0.2766 | 0.124 |
Neuropilin2 | 0.009 | 1.365 ± 0.262 | 0.9225 | 2.71 ± 0.4512 | 0.0073 |
Arterial | |||||
Ephrin-B2 | <0.0001 | 2.768 ± 0.489 | 0.0150 | 3.557 ± 0.558 | 0.0003 |
VEGF-R2 | <0.0001 | 1.388 ± 0.2069 | 0.4941 | 2.325 ± 0.2745 | 0.0001 |
Jagged1 | 0.0001 | 2.625 ± 0.4426 | 0.0079 | 2.622 ± 0.457 | 0.0080 |
Dll4 | 0.0005 | 1.29 ± 0.2524 | 0.8682 | 2.054 ± 0.4052 | 0.0187 |
Hey2 | <0.0001 | 2.786 ± 0.3775 | 0.0034 | 2.726 ± 0.5887 | 0.0047 |
Neuropilin1 | <0.0001 | 1.388 ± 0.2069 | 0.4941 | 2.325 ± 0.2745 | 0.0001 |
Notch-1 | <0.0001 | 2.062 ± 0.2682 | 0.0143 | 2.002 ± 0.3841 | 0.0225 |
CD44 | 0.0001 | 4.419 ± 0.5585 | 0.0051 | 3.325 ± 0.5885 | 0.0849 |
Unc5b | 0.0015 | 6.298 ± 1.23 | 0.0034 | 4.102 ± 1.635 | 0.1417 |
*, 1-way ANOVA; **, Dunnett’s post-hoc test.