Table 2.
Pooled results of subgroup analysis.
| Category | SEN[95%CI] | SPE[95%CI] | PLR[95%CI] | NLR[95%CI] | DOR[95%CI] | AUC | |
|---|---|---|---|---|---|---|---|
| Age (mean) | ≥60 | 0.81[0.72, 0.89] | 0.81[0.73, 0.87] | 4.14[2.99, 5.74] | 0.25[0.17, 0.37] | 21.30[12.52, 36.23] | 0.90 |
| <60 | 0.37[0.23, 0.54] | 0.76[0.70, 0.81] | 1.47[1.03, 2.09] | 0.82[0.67, 1.01] | 1.84[1.02, 3.34] | 0.72 | |
| Imaging | CT | 0.75[0.65, 0.82] | 0.87[0.79, 0.93] | 5.66[3.29, 9.74] | 0.29[0.16, 0.55] | 19.42[7.53, 50.16] | — |
| MR | 0.30[0.25, 0.34] | 0.78[0.75, 0.81] | 1.68[1.12, 2.53] | 0.79[0.62, 0.99] | 2.25[1.15, 4.38] | 0.74 | |
| P (non-smooth) (%) | ≥53 | 0.83[0.76, 0.88] | 0.86[0.77, 0.92] | 5.77[3.47, 9.59] | 0.20[0.14, 0.29] | 28.78[13.92, 59.36] | — |
| <53 | 0.35[0.31, 0.40] | 0.79[0.76, 0.81] | 2.03[1.36, 3.03] | 0.65[0.48, 0.88] | 3.51[1.62, 7.58] | 0.79 | |
SEN: sensitivity; SPE: specificity; PLR: positive likelihood ratio; NLR: negative likelihood ratio; DOR: diagnostic odds ratio; AUC: area under the receiver operating characteristic curve.