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. 2017 Nov 13;7:15443. doi: 10.1038/s41598-017-15749-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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WBSCR22 knockdown sensitized CRC cells to oxaliplatin. (A) Cell proliferation assays of the shCon and shRNA1 treated CRC cells upon oxaliplatin treatment. The IC₅₀ value of each cell line was indicated. The results were the representative of at least three independent experiments and the results were expressed as the mean ± SD. (B) Colony formation of the shCon and shRNA1 treated cells in the presence of oxaliplatin. (C) Quantification of the colony formation of the shCon and shRNA1 treated cells. The results were expressed as the mean ± SD.