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. 2017 Nov 13;7:15443. doi: 10.1038/s41598-017-15749-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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WBSCR22 knockdown increased the oxaliplatin-induced apoptosis in CRC cells. (A,B) Cellular apoptosis rate was detected by annexinV-PI assay after oxaliplatin treatment for 48 hours. The rate of apoptosis was indicated. *p < 0.05 (shRNA1 v.s. shCon). The results were from three independent experiments and the data were expressed as the mean ± SD. (C) Western blot of cleaved PARP and cleaved caspase-3 in CRC cells after oxaliplatin treatment for 48 hours.