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Light photomicrographs show the immunohistochemical expression of COX-2 in the DM (A) and DM plus VOO (B) groups (magnification, ×400). The positive staining of COX-2 is presented by a brown color of cytoplasm (arrows). Densitometry analysis of immunohistochemical photomicrographs for COX-2 was conducted. Data are expressed as a percentage of the total tissue area (C). *P=0.001 versus the vehicle and VOO groups; **P=0.004 versus the DM group;#P=0.09 versus the vehicle and VOO groups.
