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. 2017 Nov 13;7:15425. doi: 10.1038/s41598-017-15846-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The highest confidence network of genes significantly dysregulated by miR-7. The Ingenuity Pathway Analysis was carried out with the 343 genes that showed significant expression alteration by miR-7 in the MCF-10A cells. The top network identified is “Cell Cycle, Cellular Assembly and Organization, DNA Replication, Recombination, and Repair”. Shapes of red and green color represent upregulated and downregulated genes, respectively. Solid and dashed lines represent direct and indirect interactions, respectively.