Table 3. Hepatic histological scores and lipid, BA contens, and blood chemistry.
NcD (n = 4) | HcD (n = 5) | HcD+CA (n = 5) | |
---|---|---|---|
Steatosis score | 0.00 ± 0.00 | 0.40 ± 0.24 | 1.60 ± 0.24**# |
Inflammation score | 0.25 ± 0.25 | 0.80 ± 0.20 | 1.80 ± 0.20 ***## |
Ballooning score | 0.00 ± 0.00 | 0.00 ± 0.00 | 1.00 ± 0.32*# |
NAFLD score | 0.25 ± 0.25 | 1.20 ± 0.20** | 4.40 ± 0.60***### |
Hepatic TG (mg/g) | 4.2 ± 0.6 | 13.9 ± 1.4*** | 23.3 ± 0.3***## |
Hepatic FFA (µEq/g) | 3.5 ± 0.3 | 7.6 ± 0.6** | 13.8 ± 0.6***## |
Hepatic CE (mg/g) | 3.3 ± 0.4 | 25.7 ± 1.6*** | 30.6 ± 1.7***# |
Hepatic BA (µM/g) | 0.3 ± 0.02 | 0.5 ± 0.08* | 0.6 ± 0.20* |
AST (IU/L) | 41.3 ± 4.4 | 33.0 ± 1.2* | 50.5 ± 3.0*### |
ALT (IU/L) | 44.7 ± 6.3 | 33.3 ± 1.4* | 52.8 ± 9.2# |
γ-GTP (IU/L) | 50.3 ± 2.4 | 53.6 ± 2.1 | 74.0 ± 3.0****** |
ALP (IU/L) | 685.8 ± 100.7 | 983.2 ± 135.1 | 1006.6 ± 68.4* |
Values are means ± SE.
P < 0.05,
P < 0.01
P < 0.001 vs. NcD-fed µMPs;
P < 0.05,
P < 0.01
P < 0.001 vs. HcD-fed µMPs.