Table 5.

Top 6 modules from protein-protein interaction network.

Gene set	MCODE score	Nodes
Chemokine signaling pathway	31.419	CCL20, PNOC, PENK, LPAR5, C5AR1, CCR1, RGS1, ADRA2A, CXCL3, CXCL2, CCL21, CCR7, CCL19, FPR3, CCR5, CCL5, CXCL16, ADCY3, P2RY13, ADORA3, CCL16, IL8, RGS10, RGS19, CXCL1, C3, CCR2, C3AR1, CXCL12, GPR18, CXCR4, ADCY4
Cell cycle	10.303	KIF20A, PTTG1, HLA-B, CDK1, CASC5, IRF8, IRF4, CIITA, CKS2, IRF5, IRF1, IRF7, CCL4, UBE2C, KIF4A, CCNA2, AURKA, ZWINT, TOP2A, HLA-A, PTAFR, TYMS, CENPK, CCNB1, MLF1IP, HLA-C, NUSAP1, KNTC1, SGOL2, MCM4, PML, RCC2, CCNB2, TTK
B cell receptor signaling pathway	9.762	VWF, NCF4, SH3KBP1, PLEK, CD14, TNFSF13B, CD79A, BLNK, CD72, SPI1, PTPRC, KLRG1, IL2RB, PIK3CD, SYK, VAV3, CASP1, CDH5, PLCG2, FCER1G, SDC1, NCF1, INPP5D, PIK3R5, RAC2, CD22, NCF2, LYN, ACE, CYBA, DAPP1, ITGAL, HCLS1, MYD88, PRKCH, PAG1, ANPEP, CD36, THY1, SHC2, NOD2, HCK, CD2
Focal adhesion	8.852	TNS1, DLG1, NDE1, PPM1B, WDR1, RRAS, ITGB3, CNN1, SRSF1, CCND2, HNRNPD, IGF1R, TPM1, TPM2, EGFR, RHEB, TLN2, HNRNPU, PDS5B, SKA2, NUDC, PAFAH1B1, RHOQ, ABL1, CAP2, ACTG2, PPP3CB, TUBA4A, CORO1C, PAPOLA, RAF1, LAMA5, SF3B2, LAMC1, MAPRE1, ILKAP, RHOA, NDEL1, SRRM1, SRSF3, PPM1A, PPP2R5A, PPP1R12A, PPP1CB, ACTR3B, HNRNPA3, CYCS, ENAH, CLIP1, CLASP2, PPP2CB, RANBP2, PPP2R5C, VCL, ACTR3
Focal adhesion	7.414	YWHAZ, ITGA11, GNB5, KALRN, ROCK1, DNAJB4, SMAD4, S1PR3, DNAJC10, ITGB1, DNAJB6, ITGA8, ERBB2, FGF13, PDE4D, GNAS, PRKAR1A, CYFIP2, FRK, DNAJB5, CCND1, CASK, CRK, ADCY9, DLG3, HSPA4, HSPA4L, ADCY5, H2AFV, PDE3A, YAP1, PGR, MPP7, ITGA9, ROCK2, PDE8B, PCM1, PARVA, ADCY2, RAP1A, KAT7, ITGA7, DNAJA4, MAPK9, ACTN2, ZAK, CEP70, CEP63, PPM1K, MAP3K7, MPP6, COL4A5, HSP90AB1, SUGT1, STK11, PTGER3, FGFR1, ACTA2, ROR1
Regulation of actin cytoskeleton	6.25	CALD1, PLS3, FGF2, TAGLN, RHOB, CFL2, MYLK, ITGB5, WASL, JAK2, LMOD1, DSTN, PFN2, MYH11, ACTN1, PTPN11, SORBS1