Table 7.
KEGG analysis based on module D.
| GOID | GO term | Ontology source | Term P value | Nr. genes | Associated genes found |
|---|---|---|---|---|---|
| GO:0005130 | Pathogenic Escherichia coli infection | KEGG_01.03.2017 | 3.6E − 3 | 3.00 | [ABL1, RHOA, TUBA4A] |
|
| |||||
| GO:0004071 | Sphingolipid signaling pathway | KEGG_01.03.2017 | 500.0E − 6 | 5.00 | [PPP2CB, PPP2R5A, PPP2R5C, RAF1, RHOA] |
|
| |||||
| GO:0004270 | Vascular smooth muscle contraction | KEGG_01.03.2017 | 570.0E − 6 | 5.00 | [ACTG2, PPP1CB, PPP1R12A, RAF1, RHOA] |
|
| |||||
| GO:0005210 | Colorectal cancer | KEGG_01.03.2017 | 4.6E − 3 | 3.00 | [CYCS, RAF1, RHOA] |
|
| |||||
| GO:0004270 | Vascular smooth muscle contraction | KEGG_01.03.2017 | 570.0E − 6 | 5.00 | [ACTG2, PPP1CB, PPP1R12A, RAF1, RHOA] |
|
| |||||
| GO:0004510 | Focal adhesion | KEGG_01.03.2017 | 560.0E − 12 | 12.00 | [CCND2, EGFR, IGF1R, ITGB3, LAMA5, LAMC1, PPP1CB, PPP1R12A, RAF1, RHOA, TLN2, VCL] |
|
| |||||
| GO:0004611 | Platelet activation | KEGG_01.03.2017 | 610.0E − 6 | 5.00 | [ITGB3, PPP1CB, PPP1R12A, RHOA, TLN2] |
|
| |||||
| GO:0004720 | Long-term potentiation | KEGG_01.03.2017 | 6.3E − 3 | 3.00 | [PPP1CB, PPP3CB, RAF1] |
|
| |||||
| GO:0004810 | Regulation of actin cytoskeleton | KEGG_01.03.2017 | 2.1E − 6 | 9.00 | [EGFR, ENAH, ITGB3, PPP1CB, PPP1R12A, RAF1, RHOA, RRAS, VCL] |
|
| |||||
| GO:0005210 | Colorectal cancer | KEGG_01.03.2017 | 4.6E − 3 | 3.00 | [CYCS, RAF1, RHOA] |
|
| |||||
| GO:0004071 | Sphingolipid signaling pathway | KEGG_01.03.2017 | 500.0E − 6 | 5.00 | [PPP2CB, PPP2R5A, PPP2R5C, RAF1, RHOA] |
|
| |||||
| GO:0004152 | AMPK signaling pathway | KEGG_01.03.2017 | 570.0E − 6 | 5.00 | [IGF1R, PPP2CB, PPP2R5A, PPP2R5C, RHEB] |
|
| |||||
| GO:0004520 | Adherens junction | KEGG_01.03.2017 | 700.0E − 6 | 4.00 | [EGFR, IGF1R, RHOA, VCL] |
|
| |||||
| GO:0004730 | Long-term depression | KEGG_01.03.2017 | 4.6E − 3 | 3.00 | [IGF1R, PPP2CB, RAF1] |
|
| |||||
| GO:0005214 | Glioma | KEGG_01.03.2017 | 5.6E − 3 | 3.00 | [EGFR, IGF1R, RAF1] |
|
| |||||
| GO:0005218 | Melanoma | KEGG_01.03.2017 | 6.9E − 3 | 3.00 | [EGFR, IGF1R, RAF1] |
|
| |||||
| GO:0003015 | mRNA surveillance pathway | KEGG_01.03.2017 | 10.0E − 6 | 6.00 | [PAPOLA, PPP1CB, PPP2CB, PPP2R5A, PPP2R5C, SRRM1] |
|
| |||||
| GO:0004071 | Sphingolipid signaling pathway | KEGG_01.03.2017 | 500.0E − 6 | 5.00 | [PPP2CB, PPP2R5A, PPP2R5C, RAF1, RHOA] |
|
| |||||
| GO:0004114 | Oocyte meiosis | KEGG_01.03.2017 | 63.0E − 6 | 6.00 | [IGF1R, PPP1CB, PPP2CB, PPP2R5A, PPP2R5C, PPP3CB] |
|
| |||||
| GO:0004152 | AMPK signaling pathway | KEGG_01.03.2017 | 570.0E − 6 | 5.00 | [IGF1R, PPP2CB, PPP2R5A, PPP2R5C, RHEB] |
|
| |||||
| GO:0004261 | Adrenergic signaling in cardiomyocytes | KEGG_01.03.2017 | 140.0E − 6 | 6.00 | [PPP1CB, PPP2CB, PPP2R5A, PPP2R5C, TPM1, TPM2] |
|
| |||||
| GO:0004730 | Long-term depression | KEGG_01.03.2017 | 4.6E − 3 | 3.00 | [IGF1R, PPP2CB, RAF1] |
|
| |||||
| GO:0005210 | Colorectal cancer | KEGG_01.03.2017 | 4.6E − 3 | 3.00 | [CYCS, RAF1, RHOA] |