Table 1.
Common feature pharmacophore results as generated by the HipHop.
| Hypo number | Features | Rank | Direct Hit | Partial Hit | Max fit |
|---|---|---|---|---|---|
| 1 | RHHDA | 26.307 | 1111 | 0000 | 4 |
| 2 | RHHDA | 25.624 | 1111 | 0000 | 4 |
| 3 | ZHHDA | 25.574 | 1111 | 0000 | 4 |
| 4 | RHHDA | 25.352 | 1111 | 0000 | 4 |
| 5 | RHHDA | 25.352 | 1111 | 0000 | 4 |
| 6 | HHHDA | 24.569 | 1111 | 0000 | 4 |
| 7 | RHHDA | 24.450 | 1111 | 0000 | 4 |
| 8 | HHHDA | 24.362 | 1111 | 0000 | 4 |
| 9 | ZHHDA | 24.290 | 1111 | 0000 | 4 |
| 10 | RHAA | 24.069 | 1111 | 0000 | 4 |
R: ring aromatic, H: hydrophobic, HD: hydrogen bond donor, A: hydrogen bond acceptor, Z: zinc binder.