Table 5.
Comparison of systemic involvements
| Systemic damage | With skin lesions | Without skin lesions | χ2 | P | ||
|---|---|---|---|---|---|---|
| n | Ratio (%) | n | Ratio (%) | |||
| Pulmonary interstitial fibrosis | 7 | 3.9 | 8 | 1.2 | 4.757 | 0.029* |
| Pulmonary bullae | 10 | 5.5 | 18 | 2.6 | 3.966 | 0.046* |
| Liver function damage | 8 | 4.4 | 29 | 4.2 | 0.020 | 0.889 |
| PBC | 8 | 4.4 | 34 | 4.9 | 0.074 | 0.785 |
| Renal tubular acidosis | 9 | 5.0 | 30 | 4.3 | 0.139 | 0.607 |
| Neural lesions | 10 | 5.5 | 21 | 3.0 | 2.610 | 0.106 |
| Leukopenia | 57 | 31.5 | 158 | 22.8 | 5.846 | 0.016* |
| Anemia | 11 | 6.1 | 18 | 2.6 | 5.418 | 0.020* |
| Thrombocytopenia | 28 | 15.5 | 72 | 10.4 | 3.655 | 0.056 |
| Arthritis | 42 | 23.2 | 156 | 22.5 | 0.039 | 0.843 |
Incidences of pulmonary fibrosis, pulmonary bullae, leukopenia, and anemia were significantly higher in pSS patients with mucocutaneous lesions. *P<0.05. PBC: Primary biliary cirrhosis; pSS: Primary Sjögren's syndrome.