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IL-21 administration protects T cells from exhaustion. (A) Longitudinal representation of PD-1 expression among CD8+ T cells (left) and area under the curve for PD-1+CD8+ T cells (right). (B) Longitudinal representation of the PD-1 expression on CD4+ T cells (left) and area under the curve for the PD-1+ CD4+ T cells (right).
