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. Author manuscript; available in PMC: 2018 Oct 5.
Published in final edited form as: Cell. 2017 Oct 5;171(2):358–371.e9. doi: 10.1016/j.cell.2017.09.019

Key Resources Table.

REAGENT or RESOURCE SOURCE IDENTIFIER
Antibodies
MCT1 Thermo Fisher MA5-18288AB_2539662
MCT4 Santa Cruz 50329 AB_2189333
LDHA Cell Signaling C4B5AB_2066887
LDHB Novus 3EP1565Y,AB_1109158
B-Actin Sigma-Aldrich A3854AB_262011
Bacterial and Virus Strains
Biological Samples
Blood samples This study N/A
Adjacent lung tissue This study N/A
Tumor tissue This study N/A
Chemicals, Peptides, and Recombinant Proteins
[U-13C]glucose Cambridge Isotopes CLM-1396
[U-13C]lactate Cambridge Isotopes CLM-1579
[3-13C]lactate Cambridge Isotopes CLM-1578
[U-13C]lactate Sigma- Isotech 660817
[2-13C]lactate Sigma- Isotech 589209
[2-2H]lactate Sigma- Isotech 693987
[U-13C]pyruvate Sigma- Aldritch 490717
[U-13C]alanine Cambridge Isotopes CLM-2184
Critical Commercial Assays
Deposited Data
Experimental Models: Cell Lines
Human: H460 Laboratory of Dr. J.D. Minna N/A
Human: HCC827 Laboratory of Dr. J.D. Minna N/A
Human: HCC15 Laboratory of Dr. J.D. Minna N/A
Experimental Models: Organisms/Strains
Ncr nude mice Taconic NCRNU
Oligonucleotides
MCT1 CRISPRFWD: CACCGCGTATAGTCATGATTGTTGG This paper N/A
MCT1 CRISPR REV: AAACCCAACAATCATGACTATACGC This paper N/A
MCT4 CRISPRFWD: CACCGAAGAAGACACTGACGGCCTT This paper N/A
MCT4 CRISPR REV: AAACAAGGCCGTCAGTGTCTTCTTC This paper N/A
Recombinant DNA
LentiCRISPRv2 Addgene 49535
Software and Algorithms
INCA Vanderbilt https://mfa.vueinnovations.com/
The Cancer Genome Atlas NIH https://cancergenome.nih.gov/
Other