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The mRNA expressions of (A) NEP, (B) ACE2, (C) NPR‐A, and (D) NPR‐C in renal cortex after the repeated dosing of valsartan‐(15 mg/kg) and LCZ696‐(30 mg/kg) for 8 weeks. Data were obtained in rats survived at 8 weeks. Number of animals; n = 4 in the vehicle and valsartan‐(15 mg/kg) groups, and n = 5 in the LCZ696‐(30 mg/kg) and sham groups. STNx; subtotal nephrectomy, Mean expression level of sham group was set to 1.0. **P < 0.01; Mean ± SD.
