Figure 1.

Chronic effects of everolimus on body weight, food intake, systolic blood pressure, and heart rate in DS/obese and control rats from 9 to 13 weeks of age. (A, B) Body weight and food intake were measured weekly. (C, D) Systolic blood pressure and heart rate were measured once every week by the tail‐cuff method. Values are presented as means ± SEM for animals. [n = 8, 10, 7, and 12 for Cont, Cont + Eve, MetS, and MetS + Eve]. *P < 0.05 versus Cont, †P < 0.05 versus Cont+Eve, ‡P < 0.05 versus MetS.