Fig. 2.
Effects of ICV injection of PACAP6-38 on leptin induced-increase in white adipose tissue sympathetic nerve activity (WAT-SNA). Representative neurograms (A) from recordings of WAT-SNA in each group (vehicle+vehicle, vehicle+leptin, PACAP6-38+leptin). Time-course data of change in WAT-SNA following ICV injection of leptin (B). WAT-SNA changes are expressed as mean±SEM. ICV injection of vehicle or PACAP6-38 was given 15 min before ICV injection of either vehicle or leptin. Numbers of animals used are shown in the parentheses. *P<0.05 (vehicle+vehicle vs. vehicle+leptin).