Table 2.

Recommended techniques and procedures for injection of the PCL-based collagen stimulator in lower face areas

Region	Area	Device	Technique
Lower face areas	Marionette lines and oral commissures	27 G needle	Fanning, cross-hatching and microbolus 0.05 mL maximum and 0.05–0.1 mL/bolus (total volume: 0.5 mL/side); subcutaneous
	Mental crease	25–27 G needle	Linear threading technique and retrograde injection 0.05 mL/thread (total volume: 0.3–0.4 mL); subcutaneous
	Chin	25–27 G needle	Bolus or linear retrograde injection 0.5 mL/side (1 mL average); supraperiosteal
	PJS and jaw line	27 G needle or 25–27 G cannula	Fanning injection (PJS area) 0.3–0.6 mL or more; supraperiosteal Vectoring-like injection and fanning (jaw line) 0.02–0.03 mL/vector; subcutaneous Mandibular angular multiple boluses 0.1 mL; supraperiosteal

Abbreviations: PCL, polycaprolactone; PJS, prejowl sulcus.