. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: J Am Geriatr Soc. 2016 Dec 19;65(3):511–519. doi: 10.1111/jgs.14552

Table 3.

Odds of Developing Dementia or MCI When Weight Trajectory Characteristics Examined Simultaneously

Weight Measure^a	Unadjusted score (95% CI)	Age, education, clinic adjusted OR (95% CI)	Fully adjusted^b OR (95% CI)
Slope of weight change from baseline to Year 20
Per 0.5 kg/year decrease in weight)	1.32 (1.16, 1.51)	1.27 (1.11, 1.45)	1.16 (1.0, 1.33)
Weight variability (RMSPE) ^c
Per ≈1% average deviation from predicted curve	1.08 (1.01, 1.15)	1.09 (1.02, 1.16)	1.05 (0.98, 1.13)

Models include both weight measures simultaneously.

Includes age, education, clinic, depression, and walking speed (quartiles).

Variability of weight calculated using the root mean square percentage error (RMSPE) of the estimated linear and quadratic weight curves for each woman.