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. Author manuscript; available in PMC: 2017 Nov 14.
Published in final edited form as: Adv Funct Mater. 2017 Jul 6;27(32):1606632. doi: 10.1002/adfm.201606632

Figure 3.

Figure 3

(a) Raman spectra of the MUC1-NPs after 0 (black), 2 (red), 4 (blue) and 16 (purple) hours post incubation in 50 % mouse serum at 37 °C temperature. The Raman spectra were acquired at 0.05% laser power, 1-second exposure time and using a 5× objective. (b) The intensity of 960 cm−1 peak was plotted against incubation time showing an excellent signal stability of the SERS NPs. The error bars are the standard deviation of three independent measurements. (c), (d) The TEM images of the SERS NPs before and after 16 hours of serum exposure showing integrity of silica shell. Scale bars for inset images are 100 nm.