Table 3.

Comparison of Fertility-Related Issues for Individuals with Transgender Versus DSD Conditions

	Transgender	DSD
Inherent gonadal abnormality	No	Frequent
Medical treatments leading to infertility	Frequent	Infrequent
Surgical treatments leading to infertility	Generally only in adulthood	Frequent in childhood
Parental proxy decision-making	Yes	Yes
Medically “unnecessary” surgery for pre- or peripubertal fertility preservation	Yes	Rare
Concern about transmission of a genetic condition	No more than the general population	Yes
Gonadal type discordant with gender identity	Always	Sometimes