Figure 1.

β-LGND2 inhibits HFD-induced liver weight and serum transaminases. Male C57BL/six mice (n = 5/group) were maintained on either a rodent chow (normal diet [CON]) or high fat diet (HFD) and treated with vehicle or 30 mg/kg/day s.c. β-LGND2 for 10 weeks. Mice were sacrificed and liver weights were recorded (a). Blood was collected at sacrifice, serum separated, and serum transaminases were measured (b). Values are expressed as average ± SE. b > a and c at p < 0.05, while a and c are not statistically different