Figure 3.

β-LGND2 prevents liver pathology in HFD-fed mice. Male C57BL/six mice (n = 5/group) were maintained on a normal diet (CON) or high fat diet (HFD) and treated with vehicle or 30 mg/kg/day s.c. β-LGND2 for 10 weeks. Mice were sacrificed and liver from mice (n = 3/group) were fixed in formalin and stained with Masson trichrome stain (a) or hematoxylin and eosin (b). Arrows in (a) indicate collagen deposition and in (b) indicate inflammatory cells infiltration. (c) The sections were quantified and averages/group are represented as bar graph. b > a and c at p < 0.05, while a and c are not statistically different