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. 2016 Oct 26;1:16035. doi: 10.1038/npjgenmed.2016.35

Figure 1.

Figure 1

(a) General framework for integrating heterogeneous data types for patient stratification. In this study we focus on the three data types: clinical traits, genetic information and protein–protein interactions. Panels (be) illustrate the approach for compiling an enriched subset of candidate SNPs by utilising prior biological knowledge. Essentially, the top 200 GWAS SNPs were expanded using protein–protein interaction data, see text for details.