Table 1. Baseline patient characteristics associated with diabetes resolution for the nonredundant subset of 268 patients from the eMERGE cohort.
| Variable | No diabetes resolution | Diabetes resolution | P |
|---|---|---|---|
| No. of patients | 114 | 154 | |
| Male sex | 39 (34.2%) | 44 (28.6%) | 0.393 |
| Age at time of bariatric surgery (years) | 52.0 [45.0;59.0] | 48.0 [38.0;56.8] | 0.004 |
| Weight before bariatric surgery (pounds) | 308 [268;337] | 308 [260;374] | 0.423 |
| BMI before bariatric surgery (kg/m2) | 48.0 [43.7;55.0] | 50.5 [43.4;57.8] | 0.321 |
| Alcohol use before bariatric surgery (n=237) | 25 (25.0%) | 52 (38.0%) | 0.05 |
| Tobacco use before bariatric surgery (n=192) | 27 (33.3%) | 37 (33.3%) | 1 |
| Systolic blood pressure before bariatric surgery (mm Hg) | 136 [122;153] | 134 [122;152] | 0.649 |
| Diastolic blood pressure before bariatric surgery (mm Hg) | 74.0 [67.0;85.8] | 77.0 [68.0;86.0] | 0.452 |
| Pulse pressure before bariatric surgery (mm Hg) | 60.0 [49.2;73.8] | 59.0 [48.0;68.0] | 0.21 |
| Serum glucose before bariatric surgery(n=267) | 131 [91.0;198] | 101 [86.0;143] | 0.01 |
| Serum insulin before bariatric surgery(n=255) | 17.2 [9.80;35.3] | 23.2 [13.5;37.8] | 0.031 |
| Haemoglobin A1c before bariatric surgery (n=264) | 8.10 [7.20;9.40] | 6.70 [6.05;7.80] | <0.001 |
| Use of biguanides before bariatric surgery | 68 (59.6%) | 127 (82.5%) | <0.001 |
| Use of insulin before bariatric surgery | 84 (73.7%) | 35 (22.7%) | <0.001 |
| Use of sulfonylureas before bariatric surgery | 39 (34.2%) | 58 (37.7%) | 0.651 |
| Use of insulin-sensitising agents before bariatric surgery | 57 (50.0%) | 51 (33.1%) | 0.008 |
Abbreviation: BMI, body mass index.
Values show the median [1st; 3rd quartiles] or number of patients and percentages (%). P values are shown for χ2-test (categorical variables) and Kruskal–Wallis test (continuous variables). Rows with P values <0.05 are shown in bold. If not otherwise stated, n=268.