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. 2016 Nov 30;1:16038. doi: 10.1038/npjgenmed.2016.38

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Influence of potentially confounding clinical and demographic characteristics on the expression levels of the top 10 genes. (a) Multiple regression model generated by regressing potentially confounding clinical and demographic characteristics against the composite RNA expression levels of the top 10 genes selected by GA/kNN in the discovery cohort. (b) Graphical representation of the relative contribution of each regressor towards the total variance in composite RNA expression explained by the model.