Table 1. Discovery cohort clinical and demographic characteristics.
| Control (n=24) | AIS (n=39) | Statistic (df) | P | |
|---|---|---|---|---|
| Age (mean±s.d.) | 59.9±9.7 | 73.1±14.0 | t=−4.40 (61) | >0.001* |
| Female n (%) | 14 (58.3) | 22 (56.4) | χ 2=0.12 (1) | 0.731 |
| NIHSS (mean±s.d.) | 0±0.0 | 5.3±6.4 | t=5.17 (38) | >0.001* |
| Family history of stroke n (%) | 4 (16.7) | 15 (38.5) | χ 2=7.02 (1) | 0.008* |
| Hypertension n (%) | 7 (29.2) | 25 (64.1) | χ 2=11.2 (1) | 0.001* |
| Dyslipidaemia n (%) | 0 (0.00) | 18 (46.2) | χ 2=15.5 (1) | >0.001* |
| Diabetes n (%) | 2 (8.30) | 11 (28.2) | χ 2=3.58 (1) | 0.058 |
| Previous stroke n (%) | 2 (8.30) | 6 (15.4) | χ 2=0.67 (1) | 0.414 |
| Atrial fibrillation n (%) | 0 (0.00) | 6 (15.4) | χ 2=4.08 (1) | 0.043* |
| Myocardial infarction n (%) | 0 (0.00) | 6 (15.4) | χ 2=4.08 (1) | 0.043* |
| Hypertension medication n (%) | 8 (33.3) | 29 (74.4) | χ 2=10.3 (1) | 0.001* |
| Diabetes medication n (%) | 1 (4.20) | 7 (17.9) | χ 2=2.55 (1) | 0.111 |
| Cholesterol medication n (%) | 5 (20.8) | 17 (43.6) | χ 2=3.39 (1) | 0.066 |
| Anticoagulant or antiplatelet n (%) | 1 (4.20) | 20 (51.3) | χ 2=14.9 (1) | >0.001* |
| rtPA n (%) | 0 (0.00) | 9 (23.1) | χ 2=6.46 (1) | 0.011* |
| Current smoker n (%) | 2 (8.30) | 2 (5.13) | χ 2=0.26 (1) | 0.612 |
Abbreviations: AIS, acute ischaemic stroke; df, degrees of freedom; NIHSS, National Institutes of Health stroke scale; rtPA, recombinant tissue plasminogen activator.
*Indicates statistically significant values.