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. 2017 Nov 1;25(6):569–577. doi: 10.4062/biomolther.2017.193

Table 1.

Sepsis-induced alterations of immune system

Innate immunity Adaptive immunity
Extensive apoptotic cell death Apoptotic lymphocyte death
Endotoxin tolerance T cell anergy
Exhaustion phenotypes Exhaustion phenotypes
Release of immature myeloid cells Decreased T cell activation
Reduced pro-inflammatory cytokines Unbalanced Th polarization
Decreased antigen presentation capacity Enhanced Treg function and survival
Decreased antibody production