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Tan IIA reduced H2O2-induced cell injury in HUVECs. (A) HUVECs were subjected to Tan IIA for different concentrations for 24 h; Cell viability was measured with a CCK-8 assay kit. (B) Cells were transfected with PXR siRNA, with or without pretreatment with Tan IIA for 24 h then treatment with 400 μM H2O2 for another 3 h. Data are expressed as percentage of control, and the mean ± SD of 3 replicates. #p<0.05 compared with control group. ***p<0.001 compared with H2O2 group.
