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. Author manuscript; available in PMC: 2017 Nov 14.
Published in final edited form as: Environ Res. 2017 Mar 19;156:63–73. doi: 10.1016/j.envres.2017.03.009

Table 3.

List of industrial activity and population (< 15 years) exposed less than 4 km.

Foci Group Population (< 15) in 2011 around focus L HL NHL CNST SNST Other All
All 62473 Observed (Expected) 29 (35.87) 5 (4.61) 13 (8.58) 30 (30.53) 13 (12.71) 36 (37.94) 126 (130.24)
SIR 0.81 1.08 1.52 0.98 1.02 0.95 0.97
CI 95% (SIR) (0.54,1.16) (0.35,2.53) (0.81,2.59) (0.66,1.40) (0.54,1.75) (0.66,1.31) (0.81,1.15)
p-valuea 0.91 0.50 0.07 0.57 0.50 0.64 0.65
CI 95% ratio λyx (0.536,+∞) (0.39,+∞) (0.933,+∞) (0.679,+∞) (0.578,+∞) (0.679,+∞) (0.813,+∞)
Lowest (p-value) 46 (0.03) 9 (0.02) 14 (0.03) 40 (0.03) 19 (0.03) 48 (0.03) 147 (0.05)
Power 0.999 0.442 0.732 0.997 0.883 1.000 1.000
E 4388 Observed
(Expected)
1 (1.68) 1 (0.21) 0 (0.38) 1 (1.41) 3 (0.61) 3 (1.75) 9 (6.04)
SIRc 0.6 4.82 0.71 4.95 1.71 1.49
CId 95% (SIR) (0.02,3.33) (0.12,26.84) (0.02,3.95) (1.02,14.48) (0.35,5.00) (0.68,2.83)
p-valuea 0.80 0.19 0.75 0.02 0.24 0.14
CIb 95% ratio λyx (0.031,+∞) (0.242,+∞) (0.037,+∞) (1.445,+∞) (0.477,+∞) (0.796,+∞)
Lowest (p-value)e 5 (0.02) 2 (0.01) 3 (0.00) 5 (0.01) 3 (0.02) 5 (0.03) 11 (0.03)
Power 0.124 0.009 0.008 0.067 0.036 0.142 0.548
C 31967 Observed
(Expected)
9 (12.77) 2 (1.62) 5 (3.02) 10 (10.83) 8 (4.55) 18 (13.47) 52 (46.26)
SIR 0.70 1.23 1.66 0.92 1.76 1.34 1.12
CI 95% (SIR) (0.32,1.34) (0.15,4.45) (0.54,3.87) (0.44,1.70) (0.76,3.46) (0.79,2.11) (0.84,1.47)
p-valuea 0.89 0.49 0.18 0.64 0.07 0.11 0.19
CI 95% ratio λyx (0.358,+∞) (0.208,+∞) (0.647,+∞) (0.491,+∞) (0.911,+∞) (0.881,+∞) (0.889,+∞)
Lowest (p-value) 19 (0.04) 5 (0.02) 7 (0.03) 17 (0.04) 9 (0.03) 20 (0.04) 58 (0.04)
Power 0.887 0.110 0.262 0.813 0.426 0.897 1.000
P 14467 Observed
(Expected)
12 (9.69) 2 (1.24) 3 (2.32) 9 (8.24) 2 (3.43) 8 (10.24) 36 (35.16)
SIR 1.24 1.61 1.30 1.09 0.58 0.78 1.02
CI 95% (SIR) (0.64,2.16) (0.19,5.80) (0.27,3.78) (0.50,2.07) (0.07,2.11) (0.34,1.54) (0.72,1.42)
p-valuea 0.25 0.35 0.41 0.43 0.86 0.80 0.45
CI 95% ratio λyx (0.715,+∞) (0.277,+∞) (0.344,+∞) (0.563,+∞) (0.1,+∞) (0.382,+∞) (0.759,+∞)
Lowest (p-value) 16 (0.03) 4 (0.03) 6 (0.02) 14 (0.03) 8 (0.02) 16 (0.04) 46 (0.03)
0.736 0.106 0.187 0.676 0.253 0.808 0.999
Ce 12165 Observed
(Expected)
3 (7.24) 3 (0.92) 0 (1.72) 8 (6.13) 3 (2.57) 13 (7.59) 30 (26.17)
SIR 0.41 3.27 1.3 1.17 1.71 1.15
CI 95% (SIR) (0.09,1.21) (0.67,9.56) (0.56,2.57) (0.24,3.41) (0.91,2.93) (0.77,1.64)
p-valuea 0.97 0.06 0.26 0.46 0.03 0.22
CI 95% ratio λyx (0.111,+∞) (0.908,+∞) (0.652,+∞) (0.319,+∞) (1.039,+∞) (0.834,+∞)
Lowest (p-value) 13 (0.02) 4 (0.01) 5 (0.02) 11 (0.04) 6 (0.04) 13 (0.03) 35 (0.04)
Power 0.585 0.039 0.135 0.568 0.259 0.654 0.993
I 9847 Observed
(Expected)
8 (15.05) 1 (1.95) 6 (3.63) 11 (12.85) 4 (5.31) 11 (15.97) 41 (54.76)
SIR 0.53 0.51 1.65 0.86 0.75 0.69 0.75
CI 95% (SIR) (0.23,1.05) (0.01,2.85) (0.61,3.60) (0.43,1.53) (0.21,1.93) (0.34,1.23) (0.54,1.02)
p-valuea 0.98 0.87 0.15 0.74 0.79 0.92 0.98
CI 95% ratio λyx (0.249,+∞) (0.024,+∞) (0.722,+∞) (0.463,+∞) (0.243,+∞) (0.371,+∞) (0.549,+∞)
Lowest (p-value) 22 (0.04) 5 (0.04) 8 (0.02) 20 (0.03) 10 (0.03) 23 (0.04) 68 (0.03)
Power 0.922 0.199 0.305 0.848 0.494 0.938 1.000

Abbreviations: L = leukaemia; HL = Hodking lymphomas; NHL = non Hodking lymphomas; CNST = central nervous system tumours. SNST = sympathetic nervous system tumours.

§

E= energy industries; C= organic and inorganic chemical industries; P= pharmaceutical industries; Ce= building material industries; I= industries concerned with the incineration or valorisation of dangerous waste.

a

p-value (H0: λyx≤1; HA: λyx > 1). Assume that Y ∼ Poisson(nλy) and X ∼ Poisson(mλx). n=total population around (< 4 km) Foci; m=total population outside (≥4 km) Foci. Y = Cases around (< 4 km) Foci; X = Cases outside (≥4 km) Foci influence.

b

Exact confidence interval α=0.05 to the ratio λyx.

c

SIR=Standardize Incidence Ratio by age group with respect to Murcia Region.

d

Exact Confidence Interval α=0.05.

e

Lowest number of observed cases which would be statistical significant at the one sided 5% type one level or less test using this test. In brackets: Exact value of the one sided type one error corresponding to this limit.