Table 1.
Baseline characteristics of participants stratified by plasma galectin‐3 quintiles, ARIC, 1996‐1998
| Galectin‐3 Quintiles (ng/mL) | ||||||
|---|---|---|---|---|---|---|
| Characteristicsa | Q1 (4.4‐11.4) | Q2 (11.5‐13.3) | Q3 (13.4‐15.1) | Q4 (15.2‐17.5) | Q5 (17.6‐114.0) | P‐trend |
| N | 1973 | 2052 | 1951 | 1954 | 1986 | – |
| Age (years) | 61.4 (5.4) | 62.1 (5.6) | 62.6 (5.6) | 63.1 (5.6) | 64.4 (5.7) | <.0001 |
| Sex (% female) | 38.7 | 49.0 | 56.5 | 64.5 | 72.7 | <.0001 |
| Race (% black) | 16.3 | 19.2 | 21.2 | 24.4 | 28.2 | <.0001 |
| Diabetes | 13.9 | 13.7 | 15.7 | 17.0 | 21.8 | <.0001 |
| BMI (kg/m2) | 27.9 (4.6) | 28.1 (5.1) | 28.5 (5.3) | 29.1 (5.7) | 29.9 (6.4) | <.0001 |
| eGFR (mL/min per 1.73 m2) | 91 (13) | 89 (14) | 88 (14) | 86 (15) | 79 (21) | <.0001 |
| CRP (mg/L)b | 1.6 (0.8‐3.5) | 1.9 (0.9‐4.5) | 2.3 (1.1‐5.1) | 3.0 (1.3‐6.1) | 4.0 (1.6‐8.0) | <.0001 |
| Troponin T (ng/L)b | 5.0 (3.0‐7.0) | 5.0 (3.0‐8.0) | 5.0 (3.0‐8.0) | 4.0 (3.0‐8.0) | 6.0 (3.0‐10.0) | <.0001 |
| NT‐proBNP (pg/mL)b | 53 (26‐105) | 62 (30‐120) | 65 (33‐121) | 69 (36‐134) | 95 (47‐179) | .0005 |
ARIC, Atherosclerosis Risk in Communities study; BMI, body mass index; eGFR, estimated glomerular filtration rate; CRP, C‐reactive protein; NT‐proBNP, N‐terminal pro–B‐type natriuretic peptide.
a
Values are mean (standard deviation) for continuous variables and percentages for categorical variables unless otherwise specified.
b
Data are expressed as median (25th‐75th percentile).