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. Author manuscript; available in PMC: 2018 Nov 7.
Published in final edited form as: Structure. 2017 Nov 7;25(11):1697–1707.e5. doi: 10.1016/j.str.2017.09.008

Figure 1. Schematic of olfactomedin family domain organization and constructs used in this study.

Figure 1

(A) Distinctive domain organization among CC-containing olfactomedin subfamilies. Not shown: subfamily II (membrane-anchored); subfamily VI (collagen domain). (B) Schematic of myocilin constructs used in this study. Positions of key disease-associated mutations and cysteines are indicated. Green bar, predicted signal sequence for cellular secretion; cyan circles, predicted CC regions; red star, olfactomedin domain. See also Figure S1.