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. 2017 Nov 14;12(11):e0188087. doi: 10.1371/journal.pone.0188087

Fig 4. Knockdown of Ndufs4 in the CMT.

Fig 4

A. Fluorescent images of brain slices from mice injected with active WT-Cre virus (A) into the CMT (Co-ordinates: ML = ± 0.32; AP = -1.2; DV = 3.85, Magnification X40). B, C. Schematic figures from the Allen mouse brain atlas [24] depicting the viral spread (Image credit: Allen Institute). Reprinted from the Allen mouse brain atlas under a CC BY license, with permission from the Allen Institute, original copyright 2008. D. EC50s for ISO and HAL for the active (n = 6, black bars) and sham (n = 6, grey bars) virus injected mice in the LORR assay. E. EC50s for ISO and HAL for the active (n = 6, black bars) and sham (n = 6, grey bars) virus injected mice in the TC assay. Scale bar: 1mm. **indicates p-values <0.005, *** indicates p-values <0.001.