Table 2. Glioblastoma patient characteristics.
ProbeID | Fold change | P-value (unadjusted) |
---|---|---|
hsa-miR-107_st | -0.3050 | 0.000024 |
hsa-miR-3125_st | -0.3397 | 0.000092 |
hsa-miR-331-3p_st | -1.0500 | 0.000101 |
hp_hsa-mir-4315-2_s_st | -0.2556 | 0.000172 |
hsa-miR-548x_st | -1.2050 | 0.000204 |
hsa-miR-3126-5p_st | -0.6107 | 0.000227 |
hp_hsa-mir-885_st | 0.3883 | 0.000292 |
hsa-miR-4270_st | 1.1590 | 0.000676 |
hsa-miR-103_st | -0.3822 | 0.000705 |
hsa-miR-887_st | -0.7126 | 0.000873 |
The ten most significantly deregulated miRNAs in the 38 glioblastomas comparing STS to LTS depicted as fold change relative to LTS. Using the leave-one-out cross validation approach, the model predicted an accuracy of 78% with hsa-miR-107_st, hsa-miR-548x_st, hsa-miR-3125_st and hsa-miR-331-3p_st as optimal predictors (indicated with bold).