. Author manuscript; available in PMC: 2018 Nov 1.

Published in final edited form as: J Thorac Cardiovasc Surg. 2017 Jul 24;154(5):1590–1598.e2. doi: 10.1016/j.jtcvs.2017.04.091

Table 3.

Multiple regression model predicting optimal MAP.

Variable	Estimate	95% CI	P-value
Study 1 vs. 3	−6.03	(−8.6, −3.9)	<0.001
Study 2 vs. 3	−4.95	(−7.5, −2.4)	<0.001
Age	−0.02	(−0.1, 0.1)	0.650
Female gender	0.52	(−1.5, 2.6)	0.618
White ethnicity	−2.73	(−5.3,−0.21)	0.034
History of tobacco smoking	−0.20	(−2, 1.6)	0.823
Hypertension	1.90	(−0.39,4.2)	0.104
Ca⁺⁺ channel blocker	1.84	(−0.34, 4)	0.098
Diuretics	−1.89	(−3.8,−0.01)	0.049
Prior carotid endarterectomy	−5.55	(−10, −0.9)	0.019
Cardiopulmonary bypass duration (per 60 min)	−1.28	(−2.4, −0.19)	0.022

Final model was selected using backward selection based on AIC (Akaike Information Criterion) from baseline predictors listed in Table 1. Demographic variables (age, gender, ethnicity and smoking history) and study were kept in the model. Model R²=0.1002.