Table 2. Knockdown of BMI1 enhances HU-induced S arrest in MCF7 cells.

	CTRL	0.1 mM	0.3 mM	0.5 mM	0.8 mM	1.0 mM
	shCtrl shBMI1	shCtrl shBMI1	shCtrl shBMI1	shCtrl shBMI1	shCtrl shBMI1	shCtrl shBMI1
G1	64.6 ± 2.3 67.8 ± 0.7	59.0 ± 0.8 56.1 ± 3.0	62.3 ± 1.6 26.3 ± 3.7*	44.9 ± 4.6 20.1 ± 2.5*	29.5 ± 4.4 10.0 ± 0.2*	23.3 ± 0.6 9.8 ± 1.9*
S	19.5 ± 3.4 13.5 ± 0.8	24.4 ± 0.8 26.6 ± 1.4	26.6 ± 0.5 48.2 ± 3.1*	43.0 ± 5.6 66.7 ± 1.2*	64.2 ± 4.2 78.1 ± 1.0*	71.2 ± 1.2 80.9 ± 1.4*
G2/M	17.0 ± 1.1 18.7 ± 1.5	16.6 ± 0.8 17.2 ± 2.4*	11.1 ± 1.8 25.5 ± 0.7	12.1 ± 2.0 13.3 ± 2.1*	6.3 ± 1.0 12.0 ± 1.2	5.5 ± 0.9 9.3 ± 0.5*

Note: Cell cycle distributions were derived from three independent experiments and were presented as means ± S.E.; Ctrl: control; * p < 0.05 (in comparison to the respective cell cycle distributions of shCtrl cells)