Skip to main content
. 2017 Sep 22;8(52):89824–89836. doi: 10.18632/oncotarget.21158

Figure 4. CYP11A1 overexpression compromise trophoblast invasion and inhibit MMP-2 expression.

Figure 4

(A) The picture shows that trophoblast invasion could be inhibited by CYP11A1 overexpression, which could be rescued by flutamide treatment. (B) Testosterone treatment could inhibit trophoblast invasion. (C) Western blot result of MMP-2 shows that overexpression of CYP11A1 could inhibit MMP-2 expression, which could rescued by androgen receptor (AR) inhibitor, flutamide. The statistic result is shown in the right panel. * means P < 0.05, ** means P < 0.01, *** means P < 0.001,****means P < 0.0001.