Table 2. Baseline characteristics of CTC-negative and CTC-positive patients.
| Patients | |||
|---|---|---|---|
| CTC-negative, n=48 (%) | CTC-positive, n=9 (%) | P-value | |
|
Gender (%) Male Female |
36 (75.0) 12 (25.0) |
8 (88.9) 1 (11.1) |
0.362 |
|
Age (years) Mean ± SD |
64.2 ± 12.0 | 61.4 ± 4.2 | 0.528 |
|
Liver cirrhosis (%) Yes No |
18 (37.5) 30 (62.5) |
6 (66.7) 3 (33.3) |
0.104 |
|
Child-Pugh classification (%) A B |
13 (75.0) 5 (25.0) |
5 (83.3) 1 (16.7) |
0.950 |
|
Etiology of liver disease Alcohol# Chronic viral hepatitis# NASH Venous occlusive disease PBC with secondary AIH Cryptogenic cirrhosis None |
6 12 10 2 1 2 16 |
1 9 0 0 0 0 0 |
0.006 |
|
BCLC staging* A B |
17 1 |
5 1 |
0.446 |
|
Tumor Grading (G)§ 1 2 3 |
13 32 2 |
2 6 1 |
0.403 |
|
Tumor size (T)§ 1 2 3 |
23 13 1 |
3 5 1 |
0.410 |
|
Vascular Invasion (V)§ 0 1 2 |
30 16 1 |
5 4 0 |
0.639 |
|
Resection margin (R)§ 0 1 |
41 6 |
8 1 |
0.891 |
|
Recurrence N (%) RFS in months |
28 (58) 12.0 ± 2.5 |
8 (89) 5.0 ± 1.5 |
0.027 |
Abbreviations: SD, standard deviation; NASH, non-alcoholic steatohepatitis; PBC, primary biliary cholangitis; AIH, autoimmune hepatitis; T, tumor size; V, vascular invasion; R, resection margin. #Two patients revealed multiple risk factors. *Only applicable for cirrhotic patients. §In one patient histopathological analysis was not possible due to complete necrosis after prior treatment.