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. 2017 Aug 8;8(52):90532–90544. doi: 10.18632/oncotarget.20042

Figure 1. Shows the ECs classification according to TGCA including the most common genetic alteration in each subtype.

Figure 1

POLE: polymerase epsilon; MMR:mismatch repair; p53: tumor protein p53; PTEN: phosphatase and tensin homolog; PIK3: phosphatidylinositol-4,5-bisphosphate 3 kinase; KRAS: Kirsten rat sarcoma viral oncogene homolog; MMS: microsatellite stability; MSI: microsatellite instability; MLH: mutL homolog 1; MSH2: mutS homolg 2; MSH6: mutS homolog 6; RPL22: 60S ribosomal protein L22; ERBB2: human receptor tyrosine-protein kinase erbB-2; WNT-B: WNT-beta catenin pathway; PgR: progesteron receptor.