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. 2017 Oct 25;595(22):6869–6885. doi: 10.1113/JP275052

Figure 7. TRPV4‐dependent remodelling of F‐actin and AJs in confluent HrMVECs.

Figure 7

A, double labelling for β‐catenin and F‐actin. Combined images include DAPI staining (blue). GSK101‐induced disruption of central and cortical F‐actin was rescued by the TRPV4 antagonist (HC‐06). Scale bar = 50 μm. B, red fluorescent protein (RFP)‐actin‐transfected HrMVEC cells exposed to GSK101 (5 nm) show time‐dependent redistribution of F‐actin towards the cell nucleus. Scale bar = 50 μm. [Color figure can be viewed at wileyonlinelibrary.com]