Table 2.
Risk factors |
Univariate analysis |
Multivariate analysis |
||||
OR | 95%CI | P value | OR | 95%CI | P value | |
Significant in univariate and multivariate analysis | ||||||
Time between surgery and index colonoscopy | 1.006 | 1.003-1.010 | 0.001 | 1.007 | 1.001-1.013 | 0.027 |
Lactoferrin levels | 1.010 | 1.000-1.021 | 0.049 | 1.012 | 1.000-1.024 | 0.043 |
Significant in univariate analysis | ||||||
Subocclusive symptoms | 6.155 | 2.546-14.880 | < 0.001 | - | - | 0.180 |
No medical treatment with thiopurines | 2.611 | 1.282-5.319 | 0.008 | - | - | 0.500 |
Age at index colonoscopy | 1.028 | 1.002-1.055 | 0.033 | - | - | 0.932 |
Not significant in univariate nor multivariate analysis | ||||||
Smoking status | 1.877 | 0.912-3.861 | 0.087 | |||
B2 behavior | 1.221 | 0.619-2.408 | 0.565 | |||
B3 behavior | 0.895 | 0.454-1.767 | 0.750 | |||
Perianal disease | 1.376 | 0.632-2.996 | 0.421 | |||
Anti-TNF therapy | 0.893 | 0.443-1.799 | 0.751 | |||
C-reactive protein levels | 0.975 | 0.935-1.016 | 0.229 | |||
Calprotectin levels | 1.001 | 1.000-1.002 | 0.125 | |||
Harvey-Bradshaw index | 1.111 | 0.936-1.318 | 0.229 | |||
Disease duration | 1.002 | 1.000-1.005 | 0.089 |
OR: Odds ratio; CI: Confidence interval; B1: Non-stenosing and non-penetrating behaviour; B2: Stenosing behaviour; B1: Penetrating behaviour; TNF: Tumor necrosis factor.