Table 3.
Baseline characteristics comparison between anastomotic and non-anastomotic strictures n (%)
| Characteristic | Anastomotic strictures (n = 43) | Non-anastomotic strictures (n = 37) | P value |
| Female/male (n) | 19/24 | 22/15 | 0.173 |
| Disease duration in years (median; min-max) | 19.2 (5.7-52.1) | 16.3 (3.0-45.3) | 0.236 |
| Follow-up since 1st dilation in years (median; min-max) | 4.4 (1.3-6.8) | 2.9 (1.2-6.5) | < 0.001 |
| Time between 1st and 2nd dilation in days (median; min-max) | 453.5 (152-1362) | 368 (157-1705) | 0.796 |
| Age at index colonoscopy (mean; standard deviation) | 44.9 (± 12.2) | 39 (± 12.2) | 0.035 |
| Montreal classification | |||
| Age at diagnosis | 0.368 | ||
| A1 | 6 (14) | 4 (12.9) | |
| A2 | 29 (67.4) | 25 (80.6) | |
| A3 | 8 (18.6) | 2 (6.5) | |
| Disease location | 0.057 | ||
| L1 | 23 (53.5) | 9 (29) | |
| L2 | 1 (2.3) | 4 (12.9) | |
| L3 | 17 (39.5%) | 14 (45.2%) | |
| L1-4 | 2 (4.7%) | 3 (9.7%) | |
| L3-4 | - | 1 (3.2%) | |
| Behavior | |||
| B1 | 1 (2.3) | 4 (12.9) | 0.071 |
| B2 | 22 (51.2) | 19 (61.3) | 0.387 |
| B3 | 20 (46.5) | 8 (25.8) | 0.07 |
| Perianal disease | 12 (27.9) | 9 (29) | 0.916 |
| Smoking habits | 0.635 | ||
| Non-smoker | 22 (52.4) | 11 (44) | |
| Ex-smoker | 8 (19) | 9 (36) | |
| Current smoker | 12 (28.6) | 5 (20) | |
| Medication at index colonoscopy | |||
| Thiopurines | 23 (53.5) | 25 (67.6) | 0.200 |
| Anti-TNFα | 17 (39.5) | 19 (51.4) | 0.289 |
| Obstructive symptoms | 15 (35.7) | 10 (27.8) | 0.454 |
| C-reactive protein | 2.8 (0.3-18.4) | 6.95 (0.2-35.5) | 0.126 |
| Calprotectin | 103.5 (5.9-1356) | 283 (166-321) | 0.789 |
| Lactoferrin | 7.66 (1.05-204.4) | 10.7 (7.1-22.7) | 0.429 |
| Need to repeat dilation | 27 (62.8) | 15 (40.5) | 0.047 |
TNFα: Tumor necrosis factor α.