Table 1.
Sample characteristics
| More preterm (23–25 weeks) N=36 |
More mature (26–28 weeks) N=32 |
P value | |
|---|---|---|---|
| EGA, mean (SD), weeks | 24.4 (0.6) | 26.6 (0.8) | <0.01* |
| Birth weight, mean (SD), grams | 743 (133) | 922 (208) | <0.01* |
| IUGR, n (%) | 2 (6) | 4 (13) | 0.41 |
| Male sex, n (%) | 25 (69) | 21 (66) | 0.79 |
| Antenatal steroids | |||
| Any, n (%) | 26 (72) | 26 (81) | 0.41 |
| Complete course, n (%) | 20 (56) | 13 (41) | 0.24 |
| Antenatal magnesium sulfate, n (%) | 12 (33) | 18 (56) | 0.09 |
| Pre-eclampsia, n (%) | 2 (6) | 3 (9) | 0.66 |
| Vaginal delivery, n (%) | 13 (36) | 12 (38) | 1.00 |
| Chorioamnionitis, n (%) | 12 (33) | 11 (34) | 1.00 |
| Apgar score at 5 min, median (range) | 6 (1–8) | 6 (1–9) | 0.49 |
| CRIB-II score, median (range) | 13 (10–16) | 10 (6–14) | <0.01* |
| Inotrope use in first 72h, n (%) | 12 (33) | 7 (22) | 0.42 |
| Median MABP in first 72h, (IQR) | 32 (29–36) | 35 (32–39) | 0.01* |
| Fentanyl use in first 72h, n (%) | 13 (36) | 19 (59) | 0.09 |
| pCO2 in first 72h, mean (SD), mmHg | 49.9 (11.2) | 43.7 (8.4) | 0.01* |
| IVH | |||
| Any grade, n (%) | 14 (39) | 9 (28) | 0.44 |
| Grade III/IV, n (%) | 4 (11) | 2 (6) | 0.67 |
| Died, n (%) | 5 (14) | 1 (3) | 0.20 |